Best Vaccination Schedule

The Guardian® vaccination protocol is simple and convenient.


Dosage & Route2 mL SQ
Primary Dose12 weeks precalving
Booster Dose (Beef)
Booster Dose (Dairy)
3-6 weeks after primary dose*
3-6 weeks after primary dose*
Annual Revaccination5-7 weeks precalving
Bottle Sizes20 mL (10 doses) & 100 mL (50 doses)
Preslaughter Withdrawal60 days

*Needed only for first-time vaccination with Guardian.


Finishing the vaccination protocol before the beginning of colostrum formation ensures high levels of antibody are available to concentrate in colostrum. Vaccinating cows less than 5 weeks before calving may be too late to allow for optimal antibody levels in colostrum.


Schematic Representation of Colostrogenesis


Optimal Vaccination Schedule